Endocrine Abstracts

Background: Obesity is a common feature of women with PCOS in different ethnic cohorts. It is suggested that retinol binding protein 4 (RBP4) is a central mediator of obesity-induced insulin resistance in mice and humans. In addition, elevated serum RBP4 levels have been associated with cardiovascular risk factors and metabolic syndromes.Aim: To investigate whether serum RBP4 level is correlated with metabolic parameters, indices of insulin resistance, a...

Background: Visceral fat-derived protein named visfatin was discovered in 2005. Visfatin may improve glucose tolerance, and its plasma levels correlate strongly with the amount of visceral adipose tissue in humans. Visfatin has insulin-like metabolic effects on glucose metabolism but has a distinct binding site on insulin receptors. These findings triggered great interest for many researchers to explore the mechanism(s) of regulation of visfatin expression, and the possible re...